Causes or Risk Factors of Cervical Cancer: Systematic Literature Review
DOI:
https://doi.org/10.59059/mandub.v3i2.2403Keywords:
Cervical Cancer, Prevention, Reproductive Health, Risk Factors, Systematic Literature ReviewAbstract
Cervical cancer remains one of the leading causes of mortality among women, particularly in developing countries such as Indonesia, where prevalence is high and early detection is often delayed. This study aims to identify and synthesize the major risk factors for cervical cancer through a systematic review of both national and international literature. The core problem addressed is the lack of a comprehensive and context-relevant risk framework for Indonesian women, resulting in suboptimal preventive interventions. The proposed method is a qualitative descriptive literature review, analyzing 15 selected scientific articles based on defined inclusion criteria. Key findings indicate that age ≥35 years, high parity, early sexual activity, smoking habits, prolonged use of hormonal contraceptives, low educational attainment, and physically demanding occupations are significant determinants of increased cervical cancer risk. The synthesis of ideas shows that biological, behavioral, social, and environmental factors interact in complex ways to influence vulnerability to cervical cancer. This study concludes that cervical cancer prevention requires a multidimensional approach that integrates education, routine screening, and increased public awareness of modifiable risk factors. The findings are expected to inform more effective and context-sensitive health policy development in Indonesia.
References
Dewi, P. I. S., Pratama, A. A., & Astriani, N. M. D. Y. (2023, May). Faktor risiko kejadian kanker serviks di RSU Kertha Usada Buleleng. Jurnal Ilmu Kesehatan, 4, 199.
Syatriani, S. (2011, September). Faktor risiko kanker serviks di Rumah Sakit Umum Pemerintah Dr. Wahidin Sudirohusodo Makassar, Sulawesi Selatan. Peminatan Epidemiologi Sekolah Tinggi Ilmu Kesehatan Makassar, 9, 283.
Damayanti, I. P. (2013, May). Faktor-faktor yang berhubungan dengan kejadian kanker serviks di RSUD Arifin Achmad Pekanbaru tahun 2008–2010. Jurnal Kesehatan Komunitas, 2, 97.
Li, X., Hu, S. Y., & He, Y. (2018, October). Systematic literature review of risk factors for cervical cancer in the Chinese population. Women's Health, 14, 9. https://doi.org/10.1177/1745506518816399
Kashyap, N., Krishnan, N., Kaur, S., & Ghai, S. (2019, September). Risk factors of cervical cancer: A case-control study. National Institute of Nursing Education, 6, 314.
Braun, L. A. (2021, January). A scoping review of cervical cancer risk factors, prevention, diagnosis, and treatment in U.S. active duty military women. Elsevier, 1, 49.
Khabibah, U. (2022, June). Faktor risiko kanker serviks: Literature review. Faletehan Health Journal, 9, 177.
Khurshid, Z. (2022, August). Factors contributing to cervical cancer among women: A systematic review and meta-analysis. Systematic Review, 5, 72. https://doi.org/10.54393/pbmjv58.575
Novalia, V. (2023, February). Kanker serviks. Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh, 2, 56.
Bowden, S. (2023, March). Risk factors for human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer: An umbrella review and follow-up Mendelian randomisation studies. BMC Medicine, 1, 247.
Peirson, L. (2023, June). Screening for cervical cancer: A systematic review and meta-analysis. Systematic Review, 1, 10.
Soares, L. (2024, February). Cervical cancer and quality of life: Systematic review. Articles Review, 1, 24.
Yuliandari, I., & Masluroh. (2024, March). Analisis faktor risiko kanker serviks pada pasien kanker serviks di RSUD Kabupaten Bekasi. Jurnal Keperawatan Muhammadiyah, 9, 143.
Luvián-Morales, J. (2024, May). Risk factors for the development of cervical cancer: Analysis of the evidence. Frontiers in Oncology, 2, 7.
Oringtho, S., & Mwaka, A. D. (2024, July). Awareness of cervical cancer risk factors and preventive approaches, and perceived causes of cervical cancer among secondary school girls: A cross-sectional study in Northern Uganda. Annals of Medicine, 1, 42. https://doi.org/10.1080/07853890.2024.2374860
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